Abstract: The hydration of gas and water is used to promote the solidification of gas gas in the coal seam in the form of hydrate, which can prevent the rapid desorption of coal seam gas in the process of mining and eliminate the danger of coal and gas outburst. Therefore, this paper independently designed the experimental device for pressure-resistant hydration reaction, carried out gas hydration experiments, and investigated the effects of accelerator concentration and initial pressure on the formation of gas hydrates. The results showed that the addition of accelerator effectively increased the hydration effect but there was a limit concentration, when the accelerator concentration was between 0.1~0.3 mol/L, it would promote the hydration process, and the best effect was when the concentration reached 0.3 mol/L, and when the accelerator concentration was 0.5 mol/L, it would slow down the hydration process. The initial pressure was positively correlated with the hydration effect, and the higher the initial pressure, the faster the rate of hydration and the longer the hydration time. The monitoring of the methane component in the reaction residual gas shows that the accelerator and initial pressure can change the process of hydration, which plays a decisive role in the solidification effect of gas hydration.